Thanks for your help. 

Now In K2 Visual Studio -> General Properties, in the environment configuration everything is configured and tested (Category Server(s), smartobject server(s), ....), and I can deploy the process. But in the User Browser when I try to open Roles, Users or groups I get No connection could be made because the target machine actively refused it.   

Details:
System.Net.Sockets.SocketException: No connection could be made because the target machine actively refused it
at System.Net.Sockets.Socket.DoConnect(EndPoint endPointSnapshot, SocketAddress socketAddress)
at System.Net.Sockets.Socket.Connect(EndPoint remoteEP)
at System.Net.Sockets.Socket.Connect(IPAddress address, Int32 port)
at SourceCode.Hosting.Client.BaseAPI.BaseAPIConnection.Open(String connectionString)
at SourceCode.Workflow.Plugins.UserBrowser.UserBrowserHelper.InitializeRoleManagerServer()
at SourceCode.Workflow.Plugins.UserBrowser.SearchUsersGroups.SearchUsersGroups_Loaded(Object sender, RoutedEventArgs e)
at System.Windows.RoutedEventHandlerInfo.InvokeHandler(Object target, RoutedEventArgs routedEventArgs)
at System.Windows.EventRoute.InvokeHandlersImpl(Object source, RoutedEventArgs args, Boolean reRaised)
at System.Windows.UIElement.RaiseEventImpl(RoutedEventArgs args)
at System.Windows.UIElement.RaiseEvent(RoutedEventArgs e)
at MS.Internal.FrameworkObject.OnLoaded(RoutedEventArgs args)
at System.Windows.BroadcastEventHelper.BroadcastEvent(DependencyObject root, RoutedEvent routedEvent)
at System.Windows.BroadcastEventHelper.BroadcastLoadedEvent(Object root)
at MS.Internal.LoadedOrUnloadedOperation.DoWork()
at System.Windows.Media.MediaContext.FireLoadedPendingCallbacks()
at System.Windows.Media.MediaContext.FireInvokeOnRenderCallbacks()
at System.Windows.Media.MediaContext.RenderMessageHandlerCore(Object resizedCompositionTarget)
at System.Windows.Media.MediaContext.RenderMessageHandler(Object resizedCompositionTarget)
at System.Windows.Media.MediaContext.Resize(ICompositionTarget resizedCompositionTarget)
at System.Windows.Interop.HwndTarget.OnResize()
at System.Windows.Interop.HwndTarget.HandleMessage(Int32 msg, IntPtr wparam, IntPtr lparam)
at System.Windows.Interop.HwndSource.HwndTargetFilterMessage(IntPtr hwnd, Int32 msg, IntPtr wParam, IntPtr lParam, Boolean& handled)
at MS.Win32.HwndWrapper.WndProc(IntPtr hwnd, Int32 msg, IntPtr wParam, IntPtr lParam, Boolean& handled)
at MS.Win32.HwndSubclass.DispatcherCallbackOperation(Object o)
at System.Windows.Threading.ExceptionWrapper.InternalRealCall(Delegate callback, Object args, Boolean isSingleParameter)
at System.Windows.Threading.ExceptionWrapper.TryCatchWhen(Object source, Delegate callback, Object args, Boolean isSingleParameter, Delegate catchHandler)
at System.Windows.Threading.Dispatcher.InvokeImpl(DispatcherPriority priority, TimeSpan timeout, Delegate method, Object args, Boolean isSingleParameter)
at System.Windows.Threading.Dispatcher.Invoke(DispatcherPriority priority, Delegate method, Object arg)
at MS.Win32.HwndSubclass.SubclassWndProc(IntPtr hwnd, Int32 msg, IntPtr wParam, IntPtr lParam)
at MS.Win32.UnsafeNativeMethods.CallWindowProc(IntPtr wndProc, IntPtr hWnd, Int32 msg, IntPtr wParam, IntPtr lParam)
at MS.Win32.HwndSubclass.DefWndProcWrapper(IntPtr hwnd, Int32 msg, IntPtr wParam, IntPtr lParam)
at MS.Win32.UnsafeNativeMethods.CallWindowProc(IntPtr wndProc, IntPtr hWnd, Int32 msg, IntPtr wParam, IntPtr lParam)
at MS.Win32.HwndSubclass.SubclassWndProc(IntPtr hwnd, Int32 msg, IntPtr wParam, IntPtr lParam)
at MS.Win32.UnsafeNativeMethods.SetWindowPos(HandleRef hWnd, HandleRef hWndInsertAfter, Int32 x, Int32 y, Int32 cx, Int32 cy, Int32 flags)
at System.Windows.Interop.HwndSource.Resize(Size newSize)
at System.Windows.Interop.HwndSource.OnLayoutUpdated(Object obj, EventArgs args)
at System.Windows.ContextLayoutManager.fireLayoutUpdateEvent()
at System.Windows.ContextLayoutManager.UpdateLayout()
at System.Windows.Interop.HwndSource.SetLayoutSize()
at System.Windows.Interop.HwndSource.set_RootVisualInternal(Visual value)
at System.Windows.Interop.HwndSource.set_RootVisual(Visual value)
at System.Windows.Window.SetupInitialState(Double requestedTop, Double requestedLeft, Double requestedWidth, Double requestedHeight)
at System.Windows.Window.CreateSourceWindowImpl()
at System.Windows.Window.SafeCreateWindow()
at System.Windows.Window.ShowHelper(Object booleanBox)
at System.Windows.Window.Show()
at SourceCode.Workflow.Plugins.UserBrowser.UserBrowserHelper.ShowSearchWindow(ObjectBrowserPlugin parent)