Yes this is possible and very easy to do in fact. All you need to do is register a custom CRM plugin, pass some information to K2 and you are good to go. How you extend it is up to you, read below.

It essentially allows you to start K2 processes from CRM4.0 workflows on any CRM4.0 entity event i.e entity create, entity field update. Very cool indeed. I can't take the credit for this as the idea came from an awesome blog post which was given to me by our partner Ciber UK.

The plugin will be made available with full instructions and nice demo video to show you how it can be used in the K2 blackmarket shortly.

Hope you guys find some use for it.